Pala-Tech Canine Thyroid Chewable Tablets
Canine Thyroid Chewable Tablets by Pala-Tech provides thyroid replacement therapy for all
conditions of inadequate production of thyroid hormones in dogs. Pala-Tech Canine Thyroid Levothyroxine is FDA approved for use in dogs; however, it is a commonly
accepted practice for veterinarians to use this medication in cats.
Levothyroxine sodium acts, as does endogenous thyroxine,
to stimulate metabolism, growth, development and differentiation of tissues. It
increases the rate of energy exchange and increases the maturation rate of the
epiphyses. Levothyroxine sodium is absorbed rapidly from the gastrointestinal
tract after oral administration. Following absorption, the compound becomes
bound to the serum alpha globulin fraction.
Canine Thyroid Chewable Tablets make it easier to administer the daily dose to dogs. Administer tablets free
choice to the dog or crumble over the dog's food.
- Effective therapy with consistent clinical results
- An affordable alternative to
conventional tablets for managing canine hypothyroidism
- Very palatable chewable tablets
- Soy Protein derived roast beef/liver favoring - Safe for Food Allergy Dogs
Hypothyroidism is the generalized
metabolic disease resulting from deficiency of the thyroid hormones
levothyroxine (T4) and liothyronine (T3).
Each tablet, Pala-Tech Canine Thyroid Chewable Tablets (Levothyroxine Sodium,
USP), will provide levothyroxine (T4) as a
substrate for the physiologic deiodination to liothyronine (T3).
Administration of levothyroxine sodium alone will result in complete physiologic
Canine hypothyroidism is usually primary, i.e. due to
the atrophy of the thyroid gland. In the majority of cases the atrophy is
associated with lymphocytic thyroiditis and in the remainder it is
non-inflammatory and as of yet unknown etiology. Less than 10 percent of cases
of hypothyroidism are secondary, i.e. due to deficiency of thyroid stimulating
hormone (TSH). TSH deficiency may occur as a component of congenital
hypopituitarism or as an acquired disorder in adult dogs, in which case it is
invariably due to the growth of a pituitary tumor.
Hypothyroidism usually occurs in middle-aged and older
dogs although the condition will sometimes be seen in younger dogs of the larger
breeds. Neutered animals of either sex are also frequently affected, regardless
of age. The following are clinical signs of hypothyroidism in dogs:
- Lethargy, lack of endurance, increased sleeping
Reduced interest, alertness and excitability
Slow Heart rate, weak apex heartbeat and pulse, low voltage on ECG
Preference for warmth, low body temperature, cool skin
Increased body weight
- Still and slow movements, dragging of the front feet
Head tilt, disturbed balance, unilateral facial paralysis
- Atrophy of the epidermis, thickening of the dermis
Surface and follicular hyperkeratosis, pigmentation (skin discolorization)
Puffy face, blepharoptosis, tragic expression
Dry, coarse, sparse haircoat, slow regrowth after clipping, brittle haircoat
Retarded turnover of hair (carpet coat of boxers)
Dry, flaky skin
Excessive shedding; bald spots
Infections, particularly of the skin and ears
- Excessive grooming
Shortening of absence of estrus, lack of libido
Dry feces; occasional diarrhea
- Clinical Pathological:
Normochromic, normocytic anemia
Elevated serum creatinine phosphokinase
usual dose in dogs is 0.1mg/10 pounds of body weight. The usual dose in cats is
0.05-0.1mg per cat. The dose is maintained by periodic blood tests to determine
the T4 level. Animals with hypothyroidism are usually treated with Levothyroxine
If given at the proper dose as determined by blood tests there should be no side
effects. Overdose will result in the symptoms of thyrotoxicosis which may
include increased thirst, urination and hunger, hyperactivity, personality
change, and reduced heat tolerance.
This medication should not be used in animals allergic to it. Do not use in
animals with untreated adrenal insufficiency (Addison's disease), use with
caution in animals with high blood pressure. Use with caution when given with
warfarin, theophylline, digoxin, phenytoin and barbiturates. Give 1 hour before
or 4 hours after vitamin/mineral combinations containing iron or calcium. Always
tell your veterinarian and pharmacist what other medications your pet is taking.
There can be differences in the action of Levothyroxine when changing brands. As
a result, it may be necessary to retest T4 levels when switching brands.
Levothyroxine is contraindicated in thyrotoxicosis, acute myocardial
infarction and uncorrected adrenal insufficiency. Use in pregnant bitches
has not been evaluated.
In the event of an overdose:
Contact your veterinarian or veterinary emergency room. Symptoms of overdose (thyrotoxicosis)
may include increased thirst, urination and hunger, hyperactivity, personality
change, and reduced heat tolerance.
Keep this medication in the container it came in, tightly closed. Store tablets
at room temperature, away from excess heat, light and moisture. Do not store in
the bathroom. Throw away any medication that is outdated or no longer needed.
Federal law restricts this drug to use by
or on the order of a licensed veterinarian
Keep out of reach of children and pets.
Packaged with childproof safety cap on bottle.
How Supplied: Dosage strengths
0.1 mg to 1.0 mg. Package sizes 180 and 1000 chewable tablets. Packaged with childproof safety cap on bottle.
Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.