When using the 200 mL, 500 mL or 1000 mL pack size, use only automatic
syringe equipment. As with any injection, sterile equipment should be used.
The injection site should be cleaned and disinfected with alcohol before
injection. The rubber stopper should also be disinfected with alcohol to
prevent contamination of the contents. Mild and transient pain reactions may
be seen in some swine following subcutaneous administration.
Recommended Treatment Program
Swine: At the time of
initiating any parasite control program, it is important to treat all
breeding animals in the herd. After the initial treatment, use IVOMEC
Injection regularly as follows:
prior to farrowing, preferably 7-14 days before, to minimize infection of
7-14 days prior to breeding.
Treat 7-14 days prior to farrowing.
and need for treatments are dependent upon exposure. Treat at least two
times a year.
All weaner/feeder pigs should be treated before placement in clean quarters.
Pigs exposed to contaminated soil or pasture may need retreatment if
(1) IVOMEC Injection has a persistent drug level sufficient to control mite
infestations throughout the egg to adult life cycle. However, since the
ivermectin effect is not immediate, care must be taken to prevent
reinfestation from exposure to untreated animals or contaminated facilities.
Generally, pigs should not be moved to clean quarters or exposed to
uninfested pigs for approximately one week after treatment. Sows should be
treated at least one week before farrowing to minimize transfer of mites to
newborn baby pigs.
(2) Louse eggs are unaffected by IVOMEC Injection and may require up to
three weeks to hatch. Louse infestations developing from hatching eggs may
(3) Consult a veterinarian for aid in the diagnosis and control of internal
and external parasites of swine.
Special Minor Use
Reindeer: For the treatment
and control of warbles (Oedemagena
tarandi) in reindeer, inject
200 micrograms ivermectin per kilogram of body weight, subcutaneously.
Follow use directions for cattle as described under ADMINISTRATION.
American Bison: For the
treatment and control of grubs (Hypoderma
bovis) in American bison,
inject 200 micrograms ivermectin per kilogram of body weight,
subcutaneously. Follow use directions for cattle as described under ADMINISTRATION.
NOT FOR USE IN HUMANS.
Keep this and all drugs out of
the reach of children.
Transitory discomfort has been observed in some cattle following
subcutaneous administration. A low incidence of soft tissue swelling at the
injection site has been observed. These reactions have disappeared without
treatment. For cattle, divide doses greater than 10 mL between two injection
sites to reduce occasional discomfort or site reaction. Use sterile
equipment and sanitize the injection site by applying a suitable
disinfectant. Clean, properly disinfected needles should be used to reduce
the potential for injection site infections.
Observe cattle for injection site reactions. Reactions may be due to
clostridial infection and should be aggressively treated with appropriate
antibiotics. If injection site infections are suspected, consult your
This product is not for intravenous or intramuscular use.
Protect product from light.
IVOMEC Injection for Cattle and Swine has been developed specifically for
use in cattle, swine, reindeer, and American bison only.
This product should not be used in other animal species as severe adverse
reactions, including fatalities in dogs, may result.
Restricted Drug (California) - use only as directed.
When to Treat Cattle with Grubs
IVOMEC effectively controls all stages of cattle grubs. However, proper
timing of treatment is important. For most effective results, cattle should
be treated as soon as possible after the end of the heel fly (warble fly)
season. Destruction of Hypoderma larvae
(cattle grubs) at the period when these grubs are in vital areas may cause
undesirable host-parasite reactions including the possibility of fatalities.
lineatum when it is in the
tissue surrounding the esophagus (gullet) may cause salivation and bloat;
bovis when it is in the
vertebral canal may cause staggering or paralysis. These reactions are not
specific to treatment with IVOMEC, but can occur with any successful
treatment of grubs. Cattle should be treated either before or after these
stages of grub development. Consult your veterinarian concerning the proper
time for treatment. Cattle treated with IVOMEC after the end of the heel fly
season may be retreated with IVOMEC during the winter for internal
parasites, mange mites, or sucking lice without danger of grub-related
reactions. A planned parasite control program is recommended.
Studies indicate that when ivermectin comes in contact with soil, it readily
and tightly binds to the soil and becomes inactive over time. Free
ivermectin may adversely affect fish and certain aquatic organisms. Do not
permit water runoff from feed lots to enter lakes, streams or ponds. Do not
contaminate water by direct application or by improper disposal of drug
containers. Dispose of containers in an approved landfill or by
As with other avermectins, ivermectin is excreted in the dung of treated
animals and can inhibit the reproduction and growth of pest and beneficial
insects that use dung as a source of food and for reproduction. The
magnitude and duration of such effects are species and life-cycle specific.
When used according to label directions, the product is not expected to have
an adverse impact on populations of dung-dependent insects.