Description:
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(amoxicillin)
Veterinary Tablets
For use in dogs and cats
CAUTION: Federal law restricts this drug to use by or on the
order of a licensed veterinarian.
DESCRIPTION: Amoxi-Tabs (amoxicillin) is a semisynthetic
antibiotic with a broad spectrum of activity. It provides bactericidal activity
against a wide range of common gram-positive and gram-negative pathogens.
Chemically, it is D(-)-α-amino-p-hydroxybenzyl penicillin trihydrate.
ACTION: Amoxi-Tabs is stable in the presence of gastric acid
and may be given without regard to meals. It is rapidly absorbed after oral
administration. It diffuses readily into most body tissues and fluids with the
exception of brain and spinal fluid, except when meninges are inflamed. Most of
the amoxicillin is excreted unchanged in the urine.
Amoxicillin is similar to ampicillin in its bactericidal action against
susceptible organisms. It acts through the inhibition of biosynthesis of cell
wall mucopeptide. In vitro and/or
in vivo studies have demonstrated the susceptibility of most strains of the
following gram-positive and gram-negative bacteria: α- and β-haemolytic
streptococci, nonpenicillinase-producing staphylococci,
Streptococcus faecalis, Escherichia coli, and Proteus
mirabilis. Because it does not resist destruction by penicillinase, it is
not effective against penicillinase-producing bacteria, particularly resistant
staphylococci. All strains of Pseudomonas and most strains of Klebsiella and
Enterobacter are resistant.
INDICATIONS:
Dogs: Amoxi-Tabs are indicated in the treatment of
susceptible strains of the organisms causing the following infections:
Respiratory tract infections (tonsillitis, tracheobronchitis) due to
Staphylococcus aureus, Streptococcus spp.,
E. coli, and Proteus mirabilis.
Genitourinary tract infections (cystitis) due to
Staphylococcus aureus, Streptococcus spp., E. coli,
and Proteus mirabilis.
Gastrointestinal tract infections (bacterial gastroenteritis) due to
Staphylococcus aureus, Streptococcus spp.,
E. coli, and Proteus mirabilis.
Bacterial dermatitis due to Staphylococcus aureus,
Streptococcus spp., and Proteus mirabilis.
Soft tissue infections (abscesses, lacerations, and wounds) due to
Staphylococcus aureus, Streptococcus spp.,
E. coli, and Proteus mirabilis.
Cats: Amoxi-Tabs are indicated in the treatment of
susceptible strains of the organisms causing the following infections:
Upper respiratory tract infections due to Staphylococcus
aureus, Streptococcus spp., and E. coli.
Genitourinary tract infections (cystitis) due to
Staphylococcus aureus, Streptococcus spp., E. coli,
and Proteus mirabilis.
Gastrointestinal tract infections due to E. coli.
Skin and soft tissue infections (abscesses, lacerations, and wounds) due to
Staphylococcus aureus, Streptococcus spp.,
E. coli, and Pasteurella multocida.
As with all antibiotics, appropriate in vitro culturing
and susceptibility testing of samples taken before treatment should be
conducted.
CONTRAINDICATIONS: The use of this drug is contraindicated
in animals with a history of an allergic reaction to penicillin.
ADVERSE REACTIONS: Amoxicillin is a semisynthetic penicillin
and has the potential for producing allergic reactions. If an allergic reaction
occurs, administer epinephrine and/or steroids.
WARNING: For use in dogs and cats only.
DOSAGE AND ADMINISTRATION:
Dogs: The recommended dosage is 5 mg/lb of body weight
twice a day.
Cats: The recommended dosage is 50 mg (5-10 mg/lb) once
a day.
Dosage should be continued for 5-7 days or 48 hours after all symptoms have
subsided. If no improvement is seen in 5 days, review diagnosis and change
therapy.
Do Not Store at Temperatures Above 25°C (77°F)
HOW SUPPLIED: Amoxi-Tabs are supplied in 5 strengths: 50 mg,
100 mg, 150 mg, and 200 mg in bottles of 500 tablets; 400 mg in bottles of 250
tablets.
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