Description:
Capstar (nitenpyram) Tablets for Dogs and Cats
Complete
Capstar Product List
Directions:
A single dose of CAPSTAR should kill the adult fleas on your pet. If your pet
gets re-infested with fleas, you can safely give another dose as often as once
per day.
To give CAPSTAR Tablets, place the pill directly in your pet's mouth, or hide it
in food. If you hide the pill in food, watch closely to make sure your pet
swallows the pill. If you are not sure that your pet swallowed the pill, it is
safe to give a second pill.
Treat all infested pets in the household. Fleas can reproduce on untreated pets
and allow infestations to persist.
Active Ingredients:
CAPSTAR Tablets contain 11.4 or 57.0 mg of nitenpyram,
which belongs to the chemical class of neonicotinoids. Nitenpyram kills adult
fleas.
Warnings:
Not for human use. Keep this and all drugs out of the
reach of children.
Dosage:
CAPSTAR Tablets should be administered according to
the following schedule. Weigh your pet prior to administration to ensure
proper dosage. Do not administer to pets under 2
pounds.
Recommended Dosage Schedule
| Weight (lb) |
Tablets |
| Cats and dogs up to 25 lb |
1 tablet of CAPSTAR 11.4mg |
| Dogs over 25 lbs |
1 tablet of CAPSTAR 57.0mg |
Adverse
Reactions:
Laboratory and clinical studies showed that CAPSTAR Tablets are safe for use in
dogs, cats, puppies and kittens 4 weeks of age and older and 2 pounds of body
weight or greater.
Other Information:
CAPSTAR Tablets begin working within 30 minutes. In studies, CAPSTAR achieved
greater than 90% effectiveness against adult fleas on dogs within 4 hours and
cats within 6 hours.
CAPSTAR Tablets are safe for pregnant or nursing dogs and cats.
When using this product, you may notice that your dog or cat will start
scratching itself as fleas begin to die. The scratching behavior is temporary
and is a reaction to the fleas, not the drug.
CAPSTAR Tablets kill adult fleas that cause flea allergy dermatitis (FAD).
CAPSTAR Tablets may be used together with other products, including heartworm
preventives, corticosteroids, antibiotics, vaccines, de-worming medications,
shampoos and other flea products.
Flea Infestations on Dogs and Cats:
In addition to the common nuisance irritations associated with infestations,
fleas can be responsible for skin conditions in your pet such as flea allergy
dermatitis (FAD) in the dog and miliary dermatitis in the cat. Also, fleas
transmit other parasites, including tapeworms. The control of flea infestations
is important to your pet's health and also reduces the problems associated with
these parasites.
CAPSTAR Tablets do not have an effect on fleas in the pet's environment. You may
need to treat more than one time because immature fleas in and around the home
will continue to develop into adults that can reinfest your pet.
Alternatively, you can treat your pet or environment with an insect growth
regulator or you can treat your pet with an insect development inhibitor. Both
insect growth regulators and insect development inhibitors act by preventing the
development of immature stages of the flea. This will prevent fleas from
reinfesting your pet. Laboratory studies have shown that CAPSTAR Tablets can be
used safely with lufenuron.
The following diagram illustrates the flea's life cycle and where CAPSTAR
Tablets work:
Life Cycle of the Flea

Fleas can be a problem because they reproduce so rapidly. A single female flea
may produce up to 2,000 eggs over her lifetime. Eggs hatch and can develop into
adults within only three weeks. Adult female fleas feed by ingesting blood from
your pet and subsequently lay eggs, which drop off your pet's coat. Within days,
larvae hatch from the eggs and live undetected in your pet's surroundings, such
as the carpet, bedding and other protected areas. Flea larvae spin a cocoon,
and, when appropriately stimulated, a young adult flea emerges and jumps onto
your pet to continue the life cycle. When these new fleas are seen on your pet,
treat with CAPSTAR Tablets.
After reading this insert, if you have any questions about flea control or
medical problems associated with flea infestations, consult your veterinarian,
who is your pet's health care expert.
Frequently Asked Questions About Capstar Tablets
Q: What is Capstar?
A: Capstar is an oral tablet for
the treatment of flea infestations on dogs and cats. Capstar contains the
compound nitenpyram. Nitenpyram interferes with fleas' neurotransmission,
killing them very quickly.
Q: How quickly does Capstar
work?
A: Capstar begins working within 30
minutes. In clinical studies, Capstar achieved greater than 90 percent
effectiveness against adult fleas within 4 hours on dogs and within 6 hours on
cats.
Q: How long will Capstar last?
A: Capstar is a short-duration flea
adulticide. It does not prevent fleas from returning. A single dose
of Capstar should kill the adult fleas on the pet. If the pet gets
reinfested, it is safe to give another dose as often as once per day.
Q: How is Capstar different from
other flea products?
A: Capstar is the fastest flea
relief that does not leave pesticide residue on the pet or in the home.
Unlike topicals that can take up to 24 hours to become effective, Capstar begins
working within just 30 minutes.
Q: Is Capstar safe?
A: Capstar has a remarkable safety
profile. No adverse reactions were reported in controlled studies with
exposures up to 10 times the recommended dose. It is safe for pregnant and
nursing animals.
Q: Can young puppies and kittens
take Capstar?
A: Capstar can be used by puppies
and kittens 4 weeks of age and older and 2 pounds or greater.
Q: How often can dogs and cats use
Capstar?
A: A single dose of Capstar should
kill the adult fleas on the pet. If the pet gets reinfested with fleas, it
is safe to give another dose as often as once per day.
Q: If I am not certain a pet
actually swallowed the Capstar pill, is it safe to give another?
A: Yes. If you are not sure
that a pet swallowed the pill, it is safe to give a second pill.
Q: Can Capstar and lufenuron be
used together?
A: Studies have shown that Capstar
and lufenuron can be used safely together.
Q: Can Capstar be used in
conjunction with other products?
A: Yes. Capstar tablets may be used
with other products, including heartworm preventives, corticosteroids, antibiotics,
vaccines, de-worming medications and shampoos.
Q: Only one pet in the household
has fleas. Should all the pets in the household take Capstar?
A: Any pet that has fleas should
take Capstar. However, Capstar is only part of a total flea management
program. All pets in a household should be treated with an insect growth
regulator to prevent the development of immature stages of the flea. This
will prevent fleas from reinfesting your pet. Studies show that Capstar
can be used safely with lufenuron.
Q: What is the Novartis
recommendation for a flea management program?
A: Novartis has always recommended
that you address both aspects of the flea problem. This includes the 85%
of the flea population that are immature fleas, which are effectively controlled
by a product like lufenuron (Program Flavor Tabs) and the 5% of the flea
population that are adult fleas, which are effectively treated by an adulticide,
like nitenpyram (Capstar). In studies, lufenuron was safely used with
Capstar.
Storage Conditions:
Store at controlled room temperature, between 59° and 86°F (15-30°C).
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