Description:
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Dog Parasites:
• Control and prevention of
flea infestation (Ctenocephalides felis)
• Prevention of heartworm disease (Dirofilaria immitis)
• Treatment and control of ear mite infestation (Otodectes cynotis)
• Treatment and control of sarcoptic mange (Sarcoptes scabiei)
• Control of the American Dog Tick (Dermacentor variabilis)
Cat Parasites:
• Control and prevention of
flea infestation (Ctenocephalides felis)
• Prevention of heartworm disease (Dirofilaria immitis)
• Treatment and control of ear mite infestation (Otodectes cynotis)
• Treatment and control of intestinal worms
Roundworm (Toxocara cati)
Hookworm (Ancylostoma tubaeforme)
Once applied, Revolution enters the bloodstream
through the skin. Concentrations of Revolution in the blood and intestinal tract
prevent heartworm disease and treat gastrointestinal parasites, respectively.
Revolution selectively redistributes from blood to sebaceous glands, which are
found below the skin's surface. Revolution's presence in the sebaceous glands
and in the skin is the reservoir of drug that provides protection against fleas,
flea eggs, ticks and mites.
Revolution should be used
with caution in sick, debilitated or underweight animals.
Dogs should be tested for heartworm
disease prior to giving Revolution. If your dog tests positive for adult
heartworms, your veterinarian can recommend appropriate
treatment. Dogs infected with adult heartworms can safely be given Revolution.
Dosage for your Pet:
Your veterinarian will recommend the
appropriate dose for your dog or cat based on your animal’s body weight. You
should not administer Revolution to your dog or cat
if he/she is younger than 6 weeks of age. Revolution is available in six
separate dose strengths for dogs and cats of different weights.

What should I do if I
do not give Revolution on time or miss a dose?
If you forget to apply a monthly
dose of Revolution, immediately apply Revolution, resume monthly applications,
and notify your veterinarian.
What if I administer more
than the prescribed amount of Revolution to my dog or cat?
Contact your veterinarian if you
administer more than the prescribed amount of Revolution.
How should Revolution be
applied?

Do not massage Revolution
into the skin.
Do not apply when the hair
coat is wet.
Do not apply to broken
skin—Revolution contains alcohol.
Stiff hair, clumping of hair, hair
discoloration, or a slight powdery residue may be observed at the site in some
animals. These effects are usually temporary and do not affect the safety or
effectiveness of the product.
Can I give my pet a bath
after applying Revolution?
Yes. Studies show that effectiveness is
not reduced by bathing or immersing your pet in water two hours after
application.
When can I play with my pet
following treatment with Revolution?
You should avoid contact with
application site when wet. You may hold or play with your pet any time after the
area on which Revolution was applied is dry.
I see fleas on my dog or cat.
Is Revolution working?
Revolution kills adult fleas and
prevents flea eggs from hatching. You may occasionally see a few fleas on dogs
or cats treated with Revolution but more than 98% of adult fleas are killed
within 36 hours.
Immature stages of the flea called pupae may be
present in your pets’ environment (yard, flooring, carpet, bedding, etc.). These
pupae are not killed by parasiticides (including Revolution) and as such may
emerge as adult fleas. These adult fleas may hop onto your pet at anytime. They
must be exposed to Revolution on your dog or cat before being killed. It can
take from 3–5 weeks (or longer depending on environmental conditions) for most
fleas to complete their 4-stage life cycle (egg, larvae, pupae, and adult) and
reach the adult stage before being seen on your pet. Due to the presence of
immature flea stages in infested environments, it can take up to 2 to 3 monthly
applications for Revolution to maximally control the infestation of fleas in the
environment. Once the flea population is controlled you will be less likely to
see fleas.
I see ticks on my dog. Is
Revolution working?
Revolution controls tick infestations
only due to the American Dog Tick (Dermacentor variabilis), a tick commonly
found on dogs. There are other common species of ticks that are not killed or
controlled by Revolution. Your veterinarian can recommend
appropriate products to control or kill ticks common to your area. For the
control of
the American Dog Tick, Revolution should be applied once a month; however, your
veterinarian may recommend a second administration applied 14 days after the
first dose if your dog has a heavy tick infestation and/or recommend additional
tick control methods. It may take up to 5 days to kill the majority of ticks on
your dog.
What are the possible side
effects of Revolution?
Like all medicines, Revolution has some
side effects. The most common is hair loss
at the site of application with or without inflammation (redness, flaking) in
cats. Other side effects reported in cats and dogs include vomiting, diarrhea
with or without blood, anorexia (decreased appetite), lethargy (sluggishness),
salivation, rapid breathing,
pruritus (itching), urticaria (welts, hives), and erythema (skin redness).
Seizures and ataxia (incoordination) were observed rarely.
If you have additional questions about possible
side effects, talk to your veterinarian.
Can Revolution be given with
other medicines?
In well-controlled clinical studies,
Revolution was used safely in dogs and cats receiving other veterinary products
such as vaccines, anthelmintics, antiparasitics, antibiotics, steroids, collars,
shampoos and dips.
Tell your veterinarian about all medicines you
have given your dog or cat in the past, and any medicines that you are planning
to use with Revolution. This should include other medicines that you can get
without a prescription. Your veterinarian may want to check that all of your
dog’s or cat’s medicines can be given together.
How should Revolution be
stored?
Revolution is flammable—Keep away from
heat, sparks, open flames or other sources of ignition. Store below 30°C (86°F).
After application, empty tubes can be placed in your normal household refuse for
disposal.
What else should I know about
Revolution?
Revolution is not for use in humans. Revolution should be kept out of reach of
children. In humans, Revolution may be irritating to skin and eyes. Reactions
such as hives, itching and skin redness have been reported in humans in rare
instances. Revolution contains isopropyl alcohol and the preservative butylated
hydroxytoluene (BHT). Wash hands after use and wash off any product in contact
with the skin immediately with soap and water. In case of human ingestion
contact a doctor immediately.
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