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Description:
Pfizer Animal Health
Parasiticide-Oral
(pyrantel pamoate) Equine Anthelmintic Suspension
NADA No.: 091-739
Active Ingredient(s): STRONGID® T is a suspension of pyrantel pamoate in
a palatable caramel-flavored vehicle. Each mL contains 50 mg of pyrantel base as
pyrantel pamoate.
Indications: For the removal and control of mature infections of large
strongyles (Strongylus vulgaris, S. edentatus, S. equinus); pinworms (Oxyuris
equi); large roundworms (Parascaris equorum); and small strongyles in
horses and ponies.
Pharmacology: Pyrantel pamoate is a compound belonging to a family
classified chemically as tetrahydropyrimidines. It is a yellow, water-insoluble
crystalline salt of the tetrahydropyrimidine base and pamoic acid containing
34.7% base activity. The chemical name is E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(2-thienyl) vinyl] pyrimidine 4,4'
methylenebis [3-hydroxy-2-naphthoate] (1:1)
Dosage and Administration: Dosage and Treatment: Administer 3 mg pyrantel
base per lb of body weight (6 mL STRONGID® T per 100 lb of body weight). For
maximum control of parasitism, it is recommended that foals (2-8 months of age)
be dosed every 4 weeks. To minimize potential hazard that the mare may pose to
the foal, she should be treated 1 month prior to anticipated foaling date
followed by retreatment 10 days to 2 weeks after birth of foal. Horses over 8
months of age should be routinely dosed every 6 weeks.
Directions for Use: STRONGID® T may be administered by means of a stomach tube,
dose syringe or by mixing into the feed.
Stomach Tube: Measure the appropriate dosage of STRONGID® T and mix in the
desired quantity of water. Protect drench from direct sunlight and administer to
the animal immediately following mixing. Do not attempt to store diluted
suspension.
STRONGID® T is inactive against the common horse bot (Gastrophilus sp.).
However, STRONGID® T may be administered concurrently with carbon disulfide
observing the usual precautions with carbon disulfide.
Dose Syringe: Draw the appropriate dosage of STRONGID® T into a dose syringe
and administer to the animal. Do not expose STRONGID® T to direct sunlight.
Feed: Mix the appropriate dosage of STRONGID® T in the normal grain ration.
Fasting of animals prior to or following treatment is not required.
Precaution(s): Recommended Storage: Store below 30°C (86°F).
Caution(s): Federal law restricts this drug to use by or on the order of
a licensed veterinarian.
It is recommended that severely debilitated animals not be treated with this
preparation.
This product is a suspension and as such will separate. To insure uniform
resuspension and to achieve proper dosage, it is extremely important that the
product be shaken and stirred thoroughly before every use.
Keep out of the reach of children.
Warning(s): Not for horses or ponies intended for food.
Side Effects: Safety: STRONGID® T (pyrantel pamoate) is well tolerated
by horses and ponies of all ages. Adverse drug response was not observed when
dose rates up to 60 mg pyrantel base per lb of body weight were administered by
stomach tube nor when 3 mg base per lb was given by intratracheal injection. The
reproductive performance of pregnant mares and stud horses dosed with STRONGID®
T has not been affected.
Trial Data: Efficacy: Critical (worm-count) studies in horses
demonstrated that STRONGID® T administered at the recommended dosage was
efficacious against mature infections of Strongylus vulgaris (>90%), S.
edentatus (69%), S. equinus (>90%), Oxyuris equi (81%), Parascaris
equorum (>90%), and small strongyles (>90%).
Presentation: 60 mL and 1 quart bottles.
75-7972-00
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