Fleas can be a problem because they reproduce so rapidly. A single female flea may produce up to 2,000 eggs over her lifetime. Eggs hatch and can develop into adults within only three weeks. Adult female fleas feed by ingesting blood from your dog and subsequently lay eggs that drop off your dog's coat. Within days, larvae hatch from the eggs and live undetected in your dog's surroundings, such as the carpet, bedding and other protected areas. Flea larvae spin a cocoon, and when appropriately stimulated, a young adult flea emerges and jumps onto your dog to continue the life cycle. After biting a PROGRAM Flavor Tabs treated dog, the female flea ingests lufenuron which is deposited in her eggs. Lufenuron prevents these flea eggs from developing into mature adults. This safe and convenient approach to flea control effectively breaks the flea's life cycle and controls flea populations.

Dosage
PROGRAM Flavor Tabs are given orally, once a month, at the recommended minimum dosage of 4.5 mg lufenuron per pound (10 mg/kg) of body weight.

Recommended Dosage Schedule
Body Weight	Dose	Lufenuron Per Tablet
Up to 10 lbs.	One tablet	45.0 mg
11 to 20 lbs.	One tablet	90.0 mg
21 to 45 lbs.	One tablet	204.9 mg
46 to 90 lbs.	One tablet	409.8 mg

Dogs over 90 lbs. should receive the appropriate combination of tablets.

Once-A-Month
PROGRAM Flavor Tabs will safely and effectively control flea infestations only if administered in conjunction with a normal meal on a monthly dosing schedule. To help you remember the monthly dosing, use the enclosed reminder stickers on the appropriate dates on your calendar.

Adverse Reactions
The following adverse reactions have been reported in dogs after giving PROGRAM Flavor Tabs: vomiting, depression/lethargy, pruritus (itchy, scratchy skin), urticaria (wheals, hives), diarrhea, anorexia (loss of appetite), and skin congestion (red skin).

How Supplied
PROGRAM Flavor Tabs are available in four tablet sizes, formulated according to the weight of the dog. Each tablet size is available in color-coded packages of six tablets each.

Back to Top

PROGRAM^� (Lufenuron) ORAL SUSPENSION FOR CATS

Administration

TO ENSURE ADEQUATE ABSORPTION ALWAYS ADMINISTER PROGRAM SUSPENSION TO CATS IN CONJUNCTION WITH A NORMAL MEAL.

PROGRAM Suspension is administered by mixing into food. If the dose is not entirely consumed, re-dose once with the full recommended dose as soon as possible. In multiple cat households, each cat should be treated separately to ensure adequate dosing.

PROGRAM Suspension must be administered monthly, preferably on the same date each month in conjunction with a normal meal. To help you remember the monthly dosing, use the enclosed reminder stickers on the appropriate dates on your calendar. Treatment with PROGRAM Suspension may begin at any time of year. Treatment should continue until the end of �flea season�. If there is risk of exposure to fleas year-round, then treatment should continue the entire year without interruption. Ask your veterinarian for details concerning your geographic area and the most effective treatment schedule for your pet.

To maximize benefits from the use of PROGRAM Suspension, it is important to treat all cats within a household. All dogs within the household should be treated with PROGRAM Tablets. Fleas can reproduce on untreated cats and dogs and allow infestations to persist.

Directions For Use

Mix the entire contents of the appropriate size PROGRAM Suspension pack(s) with about two tablespoons of the cat's food. Since PROGRAM Suspension is a liquid, it mixes easily with wet food. You can make it a special treat for your cat by mixing it with your cat's favorite wet food.

Observe the cat closely to ensure the entire dose has been consumed and then provide its normal meal. Always administer PROGRAM to cats in conjunction with a normal meal as food is important for complete absorption of PROGRAM. If your cat does not consume its meal following administration of PROGRAM, try withholding the cat's food the night before to ensure it eats a meal with PROGRAM.

Some cats have special dietary needs, so be sure to consult your veterinarian before giving your cat any new foods or before withholding food overnight.

Description
PROGRAM Suspension is available in two sizes of packs for oral administration to cats and kittens according to their weight.

As an insect development inhibitor, PROGRAM does not kill adult fleas, but effectively and safely controls flea populations on your pet through a mode of action which breaks the flea's life cycle at the egg stage.

Indications
PROGRAM Suspension is labeled for use in cats and kittens, six weeks of age and older, for the control of flea populations.

Precautions
PROGRAM Suspension has no effect on adult fleas but acts to immediately break the flea life cycle by preventing eggs from developing into adults. However, pre-existing immature fleas in the cat's environment may continue to develop and emerge as adults after treatment with PROGRAM Suspension. Based on results of clinical studies, this emergence generally occurs during the first 30-60 days. Therefore, if your pet already has a flea infestation before starting PROGRAM, noticeable results may not be observed until several weeks after dosing. In cooler climates, immature fleas may take longer to complete the life cycle and emerge as adults. To speed control, traditional products that kill adult fleas may be used temporarily with PROGRAM, depending on the severity of the infestation.

If a PROGRAM-treated cat comes in contact with a flea-infested environment, adult fleas may infest the treated animal. However, these adult fleas will be unable to reproduce and will soon die off. Depending on the number of adult fleas, the temporary use of conventional adulticidal insecticides may be used to control these adult fleas. Your veterinarian can recommend the most effective treatment plan for your pet.

To ensure that your pet gets the greatest benefit from PROGRAM Suspension, you must administer the dose once a month in conjunction with a normal meal. If you miss the 30-day interval, give PROGRAM Suspension to your cat immediately and resume your monthly dosing schedule. It is important to treat all cats within the household. All dogs within the household should be treated with PROGRAM Tablets. Fleas can reproduce on untreated dogs and cats and allow infestations to persist.

The active ingredient in PROGRAM is excreted in high concentrations in the milk, however, no resulting adverse effects have been recognized.

Flea Infestations on Cats
Although other flea species may be found on cats, the cat flea (Ctenocephalides felis) is the predominant flea associated with infestations on cats in the United States. In addition to the common nuisance irritations associated with infestations, fleas can be responsible for medical problems in your pet such as miliary dermatitis, a skin reaction to flea bites. Also, fleas transmit other parasites, including tapeworms. Controlling flea infestations is important to your pet's health while also reducing the major and minor annoyances associated with these parasites.

Lufenuron, the active ingredient of PROGRAM Suspension does not kill adult fleas but effectively breaks the flea's life cycle by inhibiting egg development.

Back to Top