Anipryl 5mg, 30 Tablets

Anipryl 5mg, 30 Tablets

Sold ONLY to licensed veterinarians and pharmacies. Submit license if not already on file. Fax :: 800-640-3274
Licensed Professional Price: $101.48
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Availability: Usually Ships in 3 to 5 Business Days
Product Code: 10421


Anipryl Tablets

Canine Cognitive Dysfunction Syndrome

Pfizer Anipryl Tablets (Selegiline HCl) are for the control of clinical signs associated with canine cognitive dysfunction syndrome (CDS) and control of clinical signs associated with uncomplicated canine Pituitary Dependent Hyperadrenocorticism (PDH).

Anipryl Tablets can be prescribed by your veterinarian after a diagnosis of CDS has been determined. Anipryl comes in a convenient tablet form for easy dosing. Most dogs are prescribed one tablet each day, preferably in the morning. (Anipryl can be given with food.) It's important to administer every tablet as directed since interruption of therapy could lead to the reappearance of signs.

Cognitive Dysfunction Syndrome
Cognitive Dysfunction Syndrome (CDS) is caused by physical and chemical changes that affect the brain function in older dogs. Dogs with CDS may show signs of confusion and/or various other behavioral changes that are not a normal part of aging. This confusion can lead to a life of lonely isolation, separated from family members who have come to cherish their older dog's companionship. This can be as hard on family members as it is on the dog. Pet owners often describe their dogs as less responsive, forgetful or confused.

Pet owners report that 69 to 75% of dogs improved in at least one clinical sign after one month of Anipryl therapy. Because CDS is a syndrome of multiple signs, no two dogs will show exactly the same signs. Response to Anipryl may vary from dog to dog. The most common side effects are vomiting, diarrhea or changes in behavior such as hyperactivity and restlessness. Most side effects are mild to moderate. Consult your veterinarian before using Anipryl with other medications or with tick collars. As dogs grow older, they are likely to experience more health problems. Senior dogs should be observed more closely because changes in normal appearance, activity and behavior all can be signs that veterinary attention may be needed.

Dosage and Administration:

  • Cognitive Dysfunction Syndrome: Orally administer 0.5-1.0 mg/kg once daily, preferably in the morning.
  • Pituitary Dependent Hyperadrenocorticism: Orally administer 1 mg/kg once daily, preferably in the morning.

Contraindications: Anipryl is contraindicated in patients with known hypersensitivity to this drug. In humans, selegiline is contraindicated for use with meperidine and this contraindication is often extended to other opioids.

Keep out of reach of children. Not for human use.

  • Anipryl should not be administered at doses exceeding those recommended
  • Avoid the combination of Anipryl and selective serotonin reuptake inhibitors (e.g., fluoxetine) as well as Anipryl and tricyclic (e.g., clomipramine, amitriptyline, imipramine) or other antidepressants.
  • At least 14 days should elapse between discontinuation of Anipryl and initiation of treatment with a tricyclic antidepressant or selective serotonin reuptake inhibitor. Because of the long half-life of fluoxetine and its active metabolites, at least 5 weeks should elapse between discontinuation of fluoxetine and initiation of treatment with Anipryl.

Anipryl is not recommended for other behavior problems such as aggression. In the clinical trials, 3 dogs showed an increase in aggression while on this drug. The safety and efficacy of Anipryl has not been evaluated in dogs with debilitating systemic diseases other than PDH.

Reproductive Safety: The safety of Anipryl in breeding, pregnant and lactating bitches, and breeding dogs has not been determined.

Adverse Reactions include restlessness/agitation, vomiting, disorientation, diarrhea, diminished hearing, possible drug interaction (weakness, confusion, incoordination and "seizure-like" activity while being treated concurrently with metronidazole, prednisone, and trimethoprim sulfa), increase in destructive behavior in a dog with separation anxiety, anorexia, anemia, stiffness and polydipsia.

How Supplied: Five tablet strengths are available in blister-packs of 30 tablets each: 2 mg, 5 mg, 10 mg, 15 mg, and 30 mg. Each box contains 1 blister pack (30 tablets).

Storage: Store at controlled room temperature 20°-25°C (68°-77°F).

Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.

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