Melatonin is a hormone normally produced by the body that aids in the regulation of reproduction, mood and circadian (sleep-wake) cycles in people and animals. Production of melatonin is stimulated by darkness and inhibited by light. When Melatonin is given as a dietary supplement, it decreases the latency period to sleep, but does not affect total wake time or duration of sleep.  Melatonin is commonly given to pets in the management of anxiety and stress.

Nutri-Vet Pet Ease Chewables For Dogs are liver flavored chewable tablets to help calm and relax dogs naturally during stressful events. Contains a veterinary formulated blend of herbs and amino acids that help maintain contentment during separation, travel, and tension caused by changes in your dog's daily routine. Relieving anxiety may also curb destructive behavior and motion sickness related to the stressful situation.

Stress Away by Vet Classics is an easy to use calming aid for dogs and cats. Recommended to help reduce anxiety and tension during times of stress. Stress Away Soft Chews are also given when traveling by car plane or boat.

Safety Zone Canine Natural Herbal Calming Spray by Vet Classics is formulated to stimulate the type of canine pheromones that provide dogs and puppies with a sense of safety and well being. Your pet will find comfort in the light fresh fragrance.

Anxiety Relief Calming Formula is specially formulated to help dogs relax and stay calm during stressful situations such as travel, grooming, vet visits and to help separation anxiety.

Travel Anxiety will provide relief from the visually induced motion sickness. It will also calm them from relocation fear. It will take care of sickness, nervousness, drooling and pacing while traveling in a vehicle.

HomeoPet Pro Storm Stress helps to control Anxiety or anxiety induced conditions such as fear of thunder, fireworks, wind, loud noises, gunshots, hurricanes and tornados, storms, stormy weather and heavy thunderous rainfall.

Anxiety Relief Drops For Pets are fast-acting, non-sedating, anti-anxiety drops given to calm pets undergoing stressful situations - spraying, rescue pets, moving, vet visits, new pets, traveling. Safe, gentle, 100% natural.

HomeoPet Fireworks (Thunderstorm, Fireworks, Loud Noise) promotes a sense of calm in pets exhibiting fear, fretting, anxious or unwanted behavior.

HomeoPet Pro Storm Stress helps to control Anxiety or anxiety induced conditions such as fear of thunder, fireworks, wind, loud noises, gunshots, hurricanes and tornados, storms, stormy weather and heavy thunderous rainfall.

HomeoPet Pro Storm Stress helps to control Anxiety or anxiety induced conditions such as fear of thunder, fireworks, wind, loud noises, gunshots, hurricanes and tornados, storms, stormy weather and heavy thunderous rainfall.

VetriScience Composure Small Canine bite-sized Chews are for dogs exhibiting nervousness, hyperactivity, anxiety or responding to environmentally induced stress. It contains a combination of factors not found in other calming formulas that support balanced behavior.

Vetri-Science Composure Soft Chews are for dogs exhibiting nervousness, hyperactivity, anxiety or responding to environmentally induced stress. Composure is an advanced formula that contains a combination of factors, not found in other calming formulas, that support balanced behavior.

ProQuiet is a safe and gentle L-tryptophan formula that is helpful for maintaining a healthy nervous system and mental attitude in dogs and cats. Safe enough to use daily or can be used as needed in stressful situations - travel, holidays.

Stress Away by Vet Classics offers support to your pet during periods of anxiety, nervousness, tension or stress such as traveling, grooming, thunderstorms, or trips to the veterinarian. Contains all natural active ingredients.

ThunderSpray by Thunderworks mimics a mother's natural pheromones and contains soothing fragrances of lavender and chamomile. ThunderSpray can be used as an area spray or sprayed directly onto the ThunderShirt to allow the calming pheromones and fragrances to continue to release for an extended period of time. ThunderSpray is great for veterinary visits, grooming, crating, travel, fear of thunderstorms, pet and owner separation, anxiety of other animals or people, general fearfulness and many other stressful situations.

Composure Soft Chews are for dogs exhibiting nervousness, hyperactivity, anxiety or responding to environmentally induced stress. It contains a combination of factors, not found in other calming formulas, that support balanced behavior.

Rx Vitamins Liquid NutriCalm is a delicious, easy-to-deliver salmon flavored formula for dogs and cats exhibiting nervousness, anxiety or aggression. Formulated with pharmaceutical-grade L-Tryptophan, an essential amino acid which is converted to serotonin in the brain. L-Theanine, Valerian Root and Ashwaganda also help to soothe and relax pets naturally, effectively and safely.

Vetoquinol Zylkene is a nutritional supplement containing the milk protein casein. Casein has shown to promote relaxation of newborns after breastfeeding. Zylkene with casein helps pets cope with unusual, stressful and unpredictable situations as well as changes in their normal environment. Stressful situations that cause anxiety include kennel and cattery stays, travel, grooming and veterinary visits, new home, arrival of a new pet or baby, visitors and sudden noises and fireworks.

Anxitane Tablets significantly reduce stress related reactions in dogs and cats. As a nutraceutical, it is an attractive alternative to pharmaceuticals. Safe and without known side effects. No drowsiness and no  known interactions with other therapeutics.

Vet Classics Stress & Anxiety Soft Chews for dogs is formulated with a synergistic blend of botanicals to support calming behavior. Anxiety & Stress chews is effective for dogs exhibiting nervousness, anxiety, or because of environmental stress like traveling, boarding, or separation. Can be given long-term.

Thundershirts for dogs has a patent-pending design, Thundershirt's gentle, constant pressure has a dramatic calming effect for most dogs if they are anxious, fearful or over-excited.

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Thundershirts for dogs has a patent-pending design, Thundershirt's gentle, constant pressure has a dramatic calming effect for most dogs if they are anxious, fearful or over-excited. Based on surveys completed by over two thousand customers, over 80% of dogs show significant improvement in symptoms when using Thundershirt.

Thundershirts for dogs has a patent-pending design, Thundershirt's gentle, constant pressure has a dramatic calming effect for most dogs if they are anxious, fearful or over-excited. Based on surveys completed by over two thousand customers, over 80% of dogs show significant improvement in symptoms when using Thundershirt.

Thundershirts for dogs has a patent-pending design, Thundershirt's gentle, constant pressure has a dramatic calming effect for most dogs if they are anxious, fearful or over-excited. Based on surveys completed by over two thousand customers, over 80% of dogs show significant improvement in symptoms when using Thundershirt.

Thundershirts for dogs has a patent-pending design, Thundershirt's gentle, constant pressure has a dramatic calming effect for most dogs if they are anxious, fearful or over-excited. Based on surveys completed by over two thousand customers, over 80% of dogs show significant improvement in symptoms when using Thundershirt.

Thundershirts for dogs has a patent-pending design, Thundershirt's gentle, constant pressure has a dramatic calming effect for most dogs if they are anxious, fearful or over-excited. Based on surveys completed by over two thousand customers, over 80% of dogs show significant improvement in symptoms when using Thundershirt.

Anxitane Tablets significantly reduce stress related reactions in dogs and cats. As a nutraceutical, it is an attractive alternative to pharmaceuticals. Safe and without known side effects. No drowsiness and no  known interactions with other therapeutics.

Composure Liquid MAX is recommended for dogs and cats exposed to increased environmental stressors. An advanced formula that contains factors not found in other calming formulas that help control and reduce behavioral problems associated with stress.

Zentrol Chewable Tablets reduce stress-related behaviors in dogs, including stress anxiety related to noise phobias. Beef-flavored tablets begin working in 60 minutes. Stress-related behaviors may include panting, trembling, cowering and pacing as well as other unwanted behaviors. Anxiety behaviors can be triggered by a variety of stressful events such as thunderstorms, travel, grooming, fireworks, and veterinary visits.