(clindamycin hydrochloride)
Clintabs (clindamycin hydrochloride) is an antibiotic used to treat dental, bone and soft tissue infections in dogs and cats.
Aerobic
bacteria: Clindamycin hydrochloride is indicated
for the treatment of soft tissue infections (wounds and abscesses), dental
infections and osteomyelitis caused by susceptible strains of
Staphylococcus aureus.
Anaerobic bacteria: Clindamycin
hydrochloride is indicated for the treatment of soft tissue
infections (deep wounds and abscesses), dental infections and osteomyelitis
caused by or associated with susceptible strains of
Bacteroides fragilis, Bacteroides melaninogenicus, Fusobacterium necrophorum
and Clostridium perfringens.
Clindamycin is
an inhibitor of protein synthesis in the bacterial cell.
Contraindications:
Clintabs (clindamycin hydrochloride) Tablets are
contraindicated in animals with a history of hypersensitivity to
preparations containing clindamycin or lincomycin.
Because of potential adverse gastrointestinal effects, do
not administer to rabbits, hamsters, guinea pigs, horses, chinchillas or
ruminating animals.
Precautions:
Clintabs (clindamycin hydrochloride) Tablets should be
prescribed with caution in atopic animals.
During prolonged therapy of one month or greater, periodic
liver and kidney function tests and blood counts should be performed.
The use of clindamycin hydrochloride occasionally results in
overgrowth of non-susceptible organisms such as clostridia and yeasts.
Therefore, the administration of clindamycin hydrochloride should be avoided
in those species sensitive to the gastrointestinal effects of clindamycin. Should superinfections occur, appropriate measures
should be taken as indicated by the the clinical situation.
Patients with very severe renal disease and/or very severe
hepatic disease accompanied by severe metabolic aberrations should be dosed
with caution, and serum clindamycin levels monitored during high-dose
therapy.
Clindamycin hydrochloride has been shown to have
neuromuscular blocking properties that may enhance the action of other
neuromuscular blocking agents. Therefore, clindamycin hydrochloride should
be used with caution in animals receiving such agents.
Safety in gestating bitches or breeding males has not been
established.
Side Effects:
Side effects occasionally observed in either clinical trials
or during clinical use were vomiting and diarrhea.
Dosage and Administration:
Canine Infected Wounds, Abscesses and
Dental Infections
Oral: 2.5 mg/lb body weight every 12
hours. Duration: Treatment with clindamycin
hydrochloride products may be continued up to a maximum of 28 days if
clinical judgment indicates. Treatment of acute infections should not be
continued for more than three or four days if no response to therapy is
seen.
Dosage Schedule:
Tablets
Clintabs 25 mg, administer 1 tablet
every 12 hours for each 10 pounds of body weight.
Clintabs 75 mg, administer 1 tablet
every 12 hours for each 30 pounds of body weight.
Clintabs 150 mg, administer 1 tablet
every 12 hours for each 60 pounds of body weight.
Canine Osteomyelitis
Oral: 5.0 mg/lb body weight every 12
hours. Duration: Treatment with Clintabs (clindamycin
hydrochloride) Tablets is recommended for a minimum of 28 days. Treatment
should not be continued for longer than 28 days if no response to therapy is
seen.
Dosage Schedule:
Tablets
Clintabs 25 mg, administer 1 tablet
every 12 hours for each 5 pounds of body weight.
Clintabs 75 mg, administer 1 tablet
every 12 hours for each 15 pounds of body weight.
Clintabs 150 mg, administer 1 tablet
every 12 hours for each 30 pounds of body weight.
How Supplied:
Clintabs Tablets are available as:
25 mg tablets supplied in bottles of 400
75 mg tablets supplied in bottles of 200
150 mg tablets supplied in bottles of 100
Store at controlled room temperature 20°-25°C (68°-77°F).
Keep container tightly closed.
Federal (USA) law restricts
this drug to use by or on the order of a licensed veterinarian
For Use In Animals Only
Virbac Animal Health
