Fludrocortisone acetate is used in the treatment of Addison's Disease (adrenal insufficiency, hypoadrenocorticism) in dogs and cats. It is synthetic hormone given to treat conditions in which the adrenal gland does not produce enough of hormones.
Fludrocortisone acetate is a mineralocorticoid given for the treatment of adrenal insufficiency - Addison's Disease. Fludrocortisone acetate replaces both glucocorticoid and mineralocortical hormones, but it is a much stronger drug for the replacement of mineralocorticoroids. Mineralocorticoids play an important role in the regulation of electrolytes and water balance in the body. These hormones act on the kidney causing it to retain sodium and excrete potassium. When the adrenal gland does not make an appropriate amount of these hormones, blood sodium levels may become dangerously low, blood potassium levels may become dangerously high and the body may retain fluid. An acute episode of hypoadrenocorticism is called an Addisonian Crisis - a true medical emergency.
Small oral doses of fludrocortisone acetate produce marked sodium retention and increased urinary potassium excretion. Electrolytes and kidney function should be checked regularly while on Fludrocortisone. Over time, the dosage of fludrocortisone acetate will often have to be increased in order to maintain electrolyte levels within normal range.
Ingredients per tablet: Each tablet contains 0,1 mg fludrocortisone acetate.
Dosage and Administration:
- Dogs: Usual dose is 0.009 mg/lb once a day.
- Cats: Usual dose is 0.1 mg/cat once a day.
Plenty of fresh water should be available at all times. Fludrocortisone should not be stopped suddenly. Instead, there should be a gradual reduction in dosage before stopping this medication. Give with food to minimize stomach upset.
Do not give any other medication or supplements without first consulting your veterinarian. Drugs that may interact with Fludrocortisone include: Phenobarbital, furosemide, insulin, glipizide, phenytoin, digoxin, warfarin and aspirin.
Puppies or kittens of pets receiving fludrocortisone will need to be placed on milk replacement as this drug will be in the mother's milk.
Seek immediate veterinary attention if there is an allergic reaction - difficulty breathing; swelling of lips, tongue or face; hives. Other less immediate side effects include insomnia, nausea, vomiting, fatigue, muscle weakness, joint pain, regulating diabetes, increased hunger or thirst.
Storage: Store at room temperature away from heat and moisture.