Home > CAT >

ProZinc Insulin For Cats, 40 IU/ml, 20 ml Vial

ProZinc Insulin For Cats 40 IUmL 20mL Vial

Sold ONLY to licensed veterinarians and pharmacies. Submit license if not already on file. Fax: 800-640-3274
Cold Item MUST Ship Via Next Day. Please Select Next Day at check out.
Licensed Professional Price: $189.88
Copy of License Required [No Prescriptions Please]

Stock Status:In Stock

Product Code: 20117


ProZinc Insulin For Cats

Protamine Zinc Recombinant Human Insulin, 40 IU /ml

ProZinc insulin is a sterile aqueous protamine zinc suspension of recombinant human insulin indicated for the reduction of hyperglycemia and hyperglycemia-associated clinical signs in cats with diabetes mellitus. Diabetes is relatively common among feline diseases. Diabetes in a cat isn't curable, but with good care, kittens and cats with diabetes live long, happy lives. Understanding feline diabetes is important, so use this website to learn about feline diabetes treatment, how exercise and a feline diabetes diet may enhance diabetic cat health, and feline diabetes symptoms or signs, such as excess water consumption.

PROZINC is the first long-acting protamine zinc insulin with FDA approval specifically for use in cats with diabetes mellitus.

Each ml contains:

  • Recombinant human insulin - 40 IU
  • Protamine Sulfate - 0.466 mg
  • Zinc oxide - 0.088 mg
  • glycerin - 16.00 mg
  • Dibasic sodium phosphate, heptahydrate - 3.78 mg
  • Phenol (preservative) - 2.50 mg
  • Hydrochloric acid - 1.63 mg
  • Water for injection (maximum) - 1005 mg
pH is adjusted with hydrochloric acid and/or sodium hydroxide.



Federal law restricts this drug to use by or on the order of a licensed veterinarian

ProZinc insulin should be mixed by gently rolling the vial prior to withdrawing each dose from the vial. Using a U-40 insulin syringe, the injection should be administered subcutaneously on the back of the neck or on the side of the cat.

Always provide the Cat Owner Information Sheet with each prescription. The initial recommended ProZinc dose is 0.1 - 0.3 IU insulin/pound of body weight (0.2 - 0.7 IU/kg) every 12 hours. The dose should be given concurrently with or right after a meal. The veterinarian should re-evaluate the cat at appropriate intervals and adjust the dose based on both clinical signs and glucose nadirs until adequate glycemic control has been attained. In the effectiveness field study, glycemic control was considered adequate if the glucose nadir from a 9-hour blood glucose curve was between 80 and 150 mg/dL and clinical signs of hyperglycemia such as polyuria, polydipsia, and weight loss were improved.

Further adjustments in the dosage may be necessary with changes in the cat's diet, body weight, or concomitant medication, or if the cat develops concurrent infection, inflammation, neoplasia, or an additional endocrine or other medical disorder.

Contraindications: ProZinc insulin is contraindicated in cats sensitive to protamine zinc recombinant human insulin or any other ingredients in the ProZinc product. ProZinc insulin is contraindicated during episodes of hypoglycemia.

Warnings: User Safety: For use in cats only. Keep out of the reach of children. Avoid contact with eyes. In case of contact, immediately flush eyes with running water for at least 15 minutes. Accidental injection may cause hypoglycemia. In case of accidental injection, seek medical attention immediately. Exposure to product may induce a local or systemic allergic reaction in sensitized individuals.

Animal Safety: Owners should be advised to observe for signs of hypoglycemia (see Cat Owner Information Sheet). Use of this product, even at established doses, has been associated with hypoglycemia. An animal with signs of hypoglycemia should be treated immediately. Glucose should be given orally or intravenously as dictated by clinical signs. Insulin should be temporarily withheld and, if indicated, the dosage adjusted.

Any change in insulin should be made cautiously and only under a veterinarian's supervision. Changes in insulin strength, manufacturer, type, species (human, animal) or method of manufacture (rDNA versus animal-source insulin) may result in the need for a change in dosage.

Appropriate diagnostic tests should be performed to rule out other endocrinopathies in diabetic cats that are difficult to regulate.

Precautions: Animals presenting with severe ketoacidosis, anorexia, lethargy, and/or vomiting should be stabilized with short-acting insulin and appropriate supportive therapy until their condition is stabilized. As with all insulin products, careful patient monitoring for hypoglycemia and hyperglycemia are essential to attain and maintain adequate glycemic control and to prevent associated complications. Overdosage can result in profound hypoglycemia and death. Progestogens, certain endocrinopathies and glucocorticoids can have an antagonistic effect on insulin activity. Progestogen and glucocorticoid use should be avoided.

Reproductive Safety: The safety and effectiveness of ProZinc insulin in breeding, pregnant, and lactating cats has not been evaluated.

Use in Kittens: The safety and effectiveness of ProZinc insulin in kittens has not been evaluated.

How Supplied: ProZinc insulin is supplied as a sterile injectable suspension in 10 mL multidose vials. Each mL of ProZinc product contains 40 IU recombinant human insulin.

Storage Conditions: Store in an upright position under refrigeration at 36-46°F (2-8°C). Do not freeze. Protect from light.

Boehringer Ingelheim

Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.

Share your knowledge of this product. Be the first to write a review »