Samsyl Liver Health Support
SAMe & Silybin Dietary Supplement
Nutramax Samsyl is a patented, dietary supplement containing a
pure, stabilized, and naturally derived S-adenosylmethionine (SAMe) with a
highly bioavailable (absorbable) silybin-soy phosphatidylcholine complex used
for liver health in people.
The liver plays a key role in metabolism, mainly
transforming harmful substances into by-products for elimination from the body.
As such, the liver is continuously exposed to many toxic substances, including
free radicals. An unhealthy liver can result from a compromise in local
antioxidant capabilities (i.e. - decreased liver glutathione levels).
SAMe is a molecule synthesized by cells throughout the
body and is particularly important in liver cells (hepatocytes) because of their
central role in metabolism. SAMe has roles in cellular protection, regulating
the inflammatory response, promoting cell synthesis, and improving liver
function. As an example, low glutathione levels are common in those with
decreased liver function. SAMe, a glutathione precursor, has been shown to
increase hepatic glutathione levels, protecting hepatic tissues. Supplemental
SAMe improves hepatocellular function without cytotoxicity or significant side
Why use Samsyl versus other supplements?
Silybin is an active component of the milk thistle
extract from the fruit Silybum marianum and its absorption is enhanced
by soy phosphatidylcholine. Silybin, as found in Samsyl in the form
of Siliphos, has been shown in a pilot study to have beneficial
effects on liver function. Silybin has many different mechanisms of action.
Animal and human in vitro and in vivo studies have shown that
it protects against oxidative stress; promotes hepatocyte protein synthesis, a
mechanism for liver cell regeneration; inhibits leukotriene production, which
can be beneficial as production of leukotrienes is a component of the
inflammatory response; stimulates the flow of bile acid and the production of
bile salts which aid in digestion and absorption of nutrients; and increases
levels of glutathione. Please refer to reference list below for relevant
research and clinical-based citations.
Supplement Suggested Use:
Take 1 capsule, one to four times daily on an empty
stomach, or as directed by your physician.
CAUTION: Individuals with bipolar disorder (manic
depressive illness) should not take this or any other product containing SAMe
except under a physician's supervision.
If you are pregnant or nursing, or taking prescription
medications, consult your physician before taking this product.
If you have any condition that requires medical
attention you should always consult your physician before taking any drug or
Supplement Facts: Serving size 1
|Siliphos: Milk Thistle Extract [fruit] in a Soy Phosphatodylcholine
Packaging: 45 capsules and 120