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Chronic Kidney Disease in Dogs & Cats Last Updated: 07/10/2013 |
Chronic Kidney Disease
Chronic Kidney Disease (CKD) is a leading
cause of pet mortality. Since CKD is a common
result of aging, it is the leading cause of death among
older cats and dogs. Because the kidney is a
resilient organ and can compensate for a gradually
decreasing amount of normal nephrotic tissue, the
disease progresses slowly and exhibits few symptoms in
its early stages. Without laboratory testing it
can go unnoticed by even the most observant
veterinarians and pet owners.
Previously, when labs tests revealed
renal insufficiency, veterinarians had few options for
managing its inevitable progression. These options
included special diets to limit phosphorous or protein
intake and palliative care to provide temporary relief
from symptoms in end-stage cases. Delayed
diagnosis and limited treatment options have meant
frustration for veterinarians and heartbreak for
clients.
Chronic Kidney Disease is a progressively deteriorating,
multi-factorial condition that may involve one or more
of the following: hypertension, azotemia,
hyperphosphatemia, hypokalemia, and proteinuria.
All of which can cause a cascade of inflammatory
processes while contributing to scar tissue formation or
fibrosis,. Interventions at an early stage to
minimize the negative consequences of fibrosis are one
of the key strategies in managing progressive renal
disease.
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