Muricin (mupirocin) Ointment 2%
Dermatologic Ointment For Dogs
Muricin Ointment by Dechra is indicated for the topical treatment of canine bacterial
infections of the skin, including superficial pyoderma, caused by
susceptible strains of Staphylococcus aureus and Staphylococcus intermedius.
Directions: Prior to treatment, the lesion should be cleansed. Muricin ointment should be applied to the affected area twice a day. Apply a
sufficient amount of ointment to completely cover the infected area.
Maximum duration of treatment should not exceed 30 days.
Description: Each gram of Muricin Ointment contains 20 mg of mupirocin in a bland, water-washable
ointment base consisting of polyethylene glycol 400 and polyethylene
glycol 3350 (polyethylene glycol ointment, NF). Mupirocin is a
naturally-occurring, broad spectrum antibiotic.
Mupirocin inhibits bacterial protein synthesis by reversibly and
specifically binding to bacterial isoleucyl transfer-RNA synthetase. Due
to this mode of action, mupirocin shows no cross resistance with
chloramphenicol, erythromycin, gentamicin, lincomycin, neomycin,
novobiocin, penicillin, streptomycin, and tetracycline. Mupirocin is an
antimicrobial agent that inhibits the growth of gram-positive and
gram-negative bacteria. Bacteria susceptible to the action of mupirocin in vitro include the aerobic isolates of Staphylococcus aureus (including methicillin-resistant strains and ?-lactamase-producing strains), Staphylococcus intermedius, Staphylococcus epidermidis, other coagulase positive or negative Staphylococci, ?-hemolytic Streptococci, ? group A Streptococci (including S. pyogenes), other ? Streptococci (including S. agalactiae), group D Streptococci (including S. faecalis and S. faecium), group Viridans Streptococci, Streptococcus
pneumoniae, Corynebacterium hofmanii, Bacillus subtilis, Escherichia
coli, Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris,
Enterobacter cloacae, Enterobacter aerogenes, Citrobacter freundii,
Hemophilus influenzae (including ?-lactamase-producing strains), Neisseria gonorrheae (including ?-lactamase-producing strains), Neisseria meningitidis, Branhamella catarrhalis and Pasteurella multocida, and the anaerobic isolates of Peptostreptococcus anaerobius, Clostridium difficile, and Clostridium sporogenes.
Contraindications: This drug is contraindicated in animals with a history of sensitivity reactions to any of its components.
Warnings: Because of the potential
hazard of nephrotoxicity due to the polyethylene glycol content of the
base, care should be exercised when using this product in treating
extensive deep lesions where absorption of large quantities of
polyethylene glycol is possible.
Safety of use in pregnant or breeding animals has not been determined.
Muricin Ointment is not for ophthalmic use.
Adverse Reactions: No adverse
reactions have been reported with this product. If a skin reaction such
as irritation should occur, treatment should be discontinued and
appropriate therapy instituted.
Federal law restricts this drug to use by or on the order of a licensed veterinarian
Packaging: Muricin Ointment is supplied in 15-gram tubes.
Dechra Veterinary Products
Store between 15° and 30°C (59° and 86°F).
Keep Out of Reach of Children.
Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.