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Clomicalm 5mg, 30 Tablets

Clomicalm l Separation Anxiety Treatment For Dogs

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Product Code: 17448


Clomicalm Tablets

Clomipramine hydrochloride

Clomicalm Tablets by Norvartis are to be used as part of a comprehensive behavioral management program to treat separation anxiety in dogs greater than 6 months of age. Inappropriate barking or destructive behavior, as well as inappropriate elimination (urination or defecation) may be alleviated by the use of Clomicalm Tabletss in conjunction with behavior modification.

Separation anxiety is a complex behavior disorder displayed when the owner (or other attachment figure) leaves the dog. The signs of separation anxiety evaluated in controlled trials were vocalization, destructive behavior, excessive salivation, and inappropriate elimination. In the absence of the owner or attachment figure, dogs with separation anxiety may exhibit one or more of these clinical signs. Although the owner (attachment figure) may inadvertently misinterpret this behavior, which only happens in their absence, as spiteful, it is thought to be the result of anxiety experienced by the dog. Punishment is not considered appropriate for a dog with separation anxiety.

Proper recognition of clinical signs, including a complete patient history and assessment of the patient's household environment, is essential to accurately diagnose and treat separation anxiety.

The use of Clomicalm Tablets should not replace appropriate behavioral and environmental management but should be used to facilitate a comprehensive behavior management program.

Clomicalm (clomipramine hydrochloride) belongs to the dibenzazepine class of tricyclic antidepressants.

  • Dogs with known hypersensitivity to clomipramine or other tricyclic antidepressants.
  • Clomicalm should not be used in male breeding dogs. Testicular hypoplasia was seen in dogs treated for 1 year at 12.5 times the maximum daily dose.
  • Clomicalm should not be given in combination, or within 14 days before or after treatment with a monoamine oxidase inhibitor [e.g., selegiline hydrochloride (L-deprenyl), amitraz].
  • Dogs with a history of seizures or concomitantly with drugs which lower the seizure threshold.
Dosage and Administration:
The recommended daily dose of Clomicalm Tabletes is 2 to 4 mg/kg/day (0.9-1.8 mg/lb/day). It can be administered as a single daily dose or divided twice daily based on patient response and/or tolerance of the side effects. It may be prudent to initiate treatment in divided doses to minimize side effects by permitting tolerance to side effects to develop or allowing the patient time to adapt if tolerance does not develop. To reduce the incidence of vomiting that may be experienced by some dogs, Clomicalm Tablets may be given with a small amount of food.

Dog Weight (lbs)... Clomicalm Per Day... No. Tablets per Day... Tablet Strength...
2.75-5.55 mg15 mg
5.6-10.910 mg25 mg
11-2220 mg120 mg
22.1-4440 mg220 mg
44.1-8880 mg180 mg
88.1-176160 mg280 mg

The specific methods of behavioral modification used in clinical trials involved desensitization and counter-conditioning techniques. Since the manifestation of separation anxiety can vary according to the individual dog, it is advised that a specific behavior modification plan be developed based on a professional assessment of each individual case.
Once the desired clinical effect is achieved and the owners have successfully instituted the appropriate behavioral modification, the dose of CLOMICALM Tablets may be reduced to maintain the desired effect or discontinued. Withdrawal side effects were not reported in studies with CLOMICALM Tablets in dogs. However, in clinical practice, it is recommended to taper the individual patient dose while continuing to monitor the dog's behavior and clinical status through the dose reduction or withdrawal period. Continued behavioral modification is recommended to prevent recurrence of the clinical signs.

How Supplied: Clomicalm Tablets are available in 5, 20, and 80 mg tablet strengths in color-coded packaging for oral administration to dogs.

Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

Novartis Animal Health

Rx Medication Sold Only To Licensed Veterinarians & Pharmacies. Current License Must Be On File Prior To Shipping.

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